Description

3-Butoxy-2,6-Difluorophenylboronic Acid is a specialized organoboron compound, specifically a boronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific difluorophenyl motifs.
• Material Science: Building block for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Research: A valuable reagent for academic and industrial R&D labs exploring new C-C bond formation methodologies and library synthesis.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	3-Butoxy-2,6-Difluorophenylboronic Acid
CAS No.	849062-15-3
Molecular Formula	C₁₀H₁₃BF₂O₃
Molecular Weight	230.02 g/mol
Synonyms	(3-Butoxy-2,6-difluorophenyl)boronic Acid; 2,6-Difluoro-3-butoxybenzeneboronic Acid; 3-Butoxy-2,6-difluorobenzeneboronic Acid; Boronic acid, B-(3-butoxy-2,6-difluorophenyl)-; 849062-15-3; 3-n-Butoxy-2,6-difluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Butoxy-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We can supply material compliant with cGMP standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.