Description

2,6-Difluoro-3-Formylphenylboronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a difluorinated aromatic ring, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of biaryl compounds, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require fluorinated aromatic components for enhanced activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic photovoltaics, where fluorination improves electronic properties.
• Chemical Biology Probes: Utilized to develop fluorescent tags, sensors, and other molecular probes that leverage boronic acid's affinity for diols.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring specific, high-purity fluorinated boronic acids.

Basic Information

Item	Details
Product Name	2,6-Difluoro-3-Formylphenylboronic Acid
CAS No.	849062-09-5
Molecular Formula	C7H5BF2O3
Molecular Weight	185.92 g/mol
Synonyms	2,6-Difluoro-3-formylbenzeneboronic acid; (2,6-Difluoro-3-formylphenyl)boronic acid; 3-Borono-2,6-difluorobenzaldehyde; 2,6-Difluorobenzaldehyde-3-boronic acid; Boronic acid, B-(2,6-difluoro-3-formylphenyl)-; 849062-09-5; 2,6-Difluoro-3-carboxaldehydephenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-Formylphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions and advanced synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.