Description

3-Methoxy-2,4,6-Trifluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, active ingredient synthesis, and specialty polymer development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in constructing novel, fluorinated herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure allows for fine-tuning of electronic properties.
• Chemical Biology & Probe Design: Utilized in the creation of molecular probes and bio-conjugation reagents for studying biological processes and diagnostics.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Methoxy-2,4,6-Trifluorophenylboronic Acid
CAS No.	849062-08-4
Molecular Formula	C7H5BF3O3
Molecular Weight	199.92 g/mol
Synonyms	(3-Methoxy-2,4,6-trifluorophenyl)boronic acid; 2,4,6-Trifluoro-3-methoxybenzeneboronic acid; Boronic acid, B-(3-methoxy-2,4,6-trifluorophenyl)-; 3-Methoxy-2,4,6-trifluorobenzeneboronic acid; 849062-08-4; AKOS005258315; FT-0698934; BRN 29348771
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2,4,6-Trifluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon/nitrogen) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.