Description

4-[(2'-Chloro-5'-(Trifluoromethyl)Phenoxy)Methyl]Phenylboronic Acid is a high-value, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Building block for creating advanced organic electronic materials used in displays and lighting.
• Polymer & Resin Modification: Enables the introduction of specific functional groups into polymer backbones to tailor properties like thermal stability, adhesion, or solubility.
• Chemical Biology & Proteomics: Serves as a handle for bioconjugation and the development of molecular probes and sensors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-[(2'-Chloro-5'-(Trifluoromethyl)Phenoxy)Methyl]Phenylboronic Acid
CAS No.	849062-05-1
Molecular Formula	C14H11BClF3O3
Molecular Weight	330.50 g/mol
Synonyms	[2-Chloro-5-(trifluoromethyl)phenoxy]methyl]phenylboronic acid; 4-[[[2-Chloro-5-(trifluoromethyl)phenoxy]methyl]phenyl]boronic acid; (4-((2-Chloro-5-(trifluoromethyl)phenoxy)methyl)phenyl)boronic acid; 4-[(2-Chloro-α,α,α-trifluoro-p-tolyloxy)methyl]benzeneboronic acid; B-[4-[[[2-Chloro-5-(trifluoromethyl)phenyl]oxy]methyl]phenyl]-Boronic acid; 849062-05-1; AKOS005258155.
EINECS	Contact for details

Quality Control

Our production of 4-[(2'-Chloro-5'-(Trifluoromethyl)Phenoxy)Methyl]Phenylboronic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthesis. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical specifications to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.