Description

2,6-Difluoro-3-isopropoxyphenylboronic acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the difluoro and isopropoxy substituents confer specific biological activity.
• Material Science Research: Serves as a monomer or building block for creating functionalized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	2,6-Difluoro-3-isopropoxyphenylboronic acid
CAS No.	849062-04-0
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,6-Difluoro-3-isopropoxyphenyl)boronic acid; 2,6-Difluoro-3-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-(2,6-difluoro-3-isopropoxyphenyl)-; 3-Isopropoxy-2,6-difluorophenylboronic acid; 849062-04-0; B-(2,6-Difluoro-3-isopropoxyphenyl)boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluoro-3-isopropoxyphenylboronic acid is produced and tested under a strict quality management system. We ensure high lot-to-lot consistency and purity, typically offering grades suitable for research and commercial-scale synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.