Description

2,6-Difluoro-3-Ethoxybenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing a difluorinated biphenyl or heterobiaryl core.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems for enhanced activity and stability.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed synthesis projects requiring precise boronic acid coupling partners.

Basic Information

Product Name	2,6-Difluoro-3-Ethoxybenzeneboronic Acid
CAS No.	849062-00-6
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(2,6-Difluoro-3-ethoxyphenyl)boronic acid; 3-Ethoxy-2,6-difluorobenzeneboronic acid; 2,6-Difluoro-3-ethoxybenzeneboronic acid; Boronic acid, B-(2,6-difluoro-3-ethoxyphenyl)-; 849062-00-6; AKOS005258315; FT-0698395; SCHEMBL15506227
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Ethoxybenzeneboronic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We are committed to meeting the stringent requirements of research and cGMP manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.