Description

3-Bromo-2-(4'-Fluorobenzyloxy)Phenylbor& CAS NO 849052-22-8 is a specialized organoboron compound, specifically a phenylboronic acid derivative, that serves as a crucial synthetic intermediate in modern organic chemistry. Its value lies in its dual functionality, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, and the bromo and benzyloxy substituents provide additional sites for further chemical elaboration. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its structural motifs for bioactivity.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials, such as those used in OLEDs and sensors.
• Cross-Coupling Reactions: Essential reagent in palladium-catalyzed Suzuki-Miyaura couplings for forming carbon-carbon bonds in complex molecule assembly.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Ligand Synthesis: Precursor for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Bromo-2-(4'-Fluorobenzyloxy)Phenylbor& CAS NO 849052-22-8
CAS No.	849052-22-8
Molecular Formula	C₁₃H₁₁BBrFO₂
Molecular Weight	324.94 g/mol
Synonyms	3-Bromo-2-[(4-fluorophenyl)methoxy]benzeneboronic acid; [3-Bromo-2-(4-fluorobenzyloxy)phenyl]boronic acid; 2-(4-Fluorobenzyloxy)-3-bromophenylboronic acid; Boronic acid, B-[3-bromo-2-[(4-fluorophenyl)methoxy]phenyl]-; 849052-22-8; 3-Bromo-2-(4-fluorobenzyloxy)phenylboronic acid; B-[3-Bromo-2-[(4-fluorophenyl)methoxy]phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-(4'-Fluorobenzyloxy)Phenylbor& CAS NO 849052-22-8 adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.