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2-Bromo-3-Ethoxy-6-Fluorophenylboronic& CAS NO 849052-19-3


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CAS No.:849052-19-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Bromo-3-Ethoxy-6-Fluorophenylboronic acid is a high-purity, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated and alkoxy-substituted aromatic structure, which enables precise cross-coupling reactions essential for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
  • Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging its halogen and fluorine substituents for bioactivity.
  • Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
  • Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
  • Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
  • Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name 2-Bromo-3-Ethoxy-6-Fluorophenylboronic acid
CAS No. 849052-19-3
Molecular Formula C8H9BBrFO3
Molecular Weight 262.87 g/mol
Synonyms (2-Bromo-3-ethoxy-6-fluorophenyl)boronic acid; 2-Bromo-3-ethoxy-6-fluorobenzeneboronic acid; Boronic acid, B-(2-bromo-3-ethoxy-6-fluorophenyl)-; 849052-19-3; AKOS025310065; BRN 9088015; FT-0698085; SCHEMBL15506211; A1-03473
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Quality Control

Every batch of our 2-Bromo-3-Ethoxy-6-Fluorophenylboronic acid undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. Our quality protocols are designed to guarantee batch-to-batch consistency, purity, and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its boronic acid nature and light-sensitive property, prolonged exposure to moisture, heat, or light should be avoided to maintain stability and potency.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%
Heavy Metals ≤20 ppm
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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