Description

1-Boc-4-(5-Aminopentyl)Piperazine is a high-purity, protected piperazine derivative featuring a Boc-protected amine and a terminal primary amine on a pentyl linker. This bifunctional structure makes it a versatile and critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by research chemists and process development scientists in the life sciences sector for creating novel drug candidates, bioconjugates, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in oncology, CNS, and antiviral research.
• Peptide Mimetic & Linker Chemistry: Used to introduce spacer arms and functional handles in peptide mimetics and for constructing bioconjugates.
• Polymer & Dendrimer Synthesis: Serves as a monomer or branching unit for creating functional polymers and dendrimers with amine termini.
• Ligand & Chelator Development: Employed in the synthesis of novel ligands for catalysis or metal chelation applications.
• Chemical Biology Probes: Useful for labeling biomolecules or creating probes for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the custom synthesis of client-specific target molecules.

Basic Information

Product Name	1-Boc-4-(5-Aminopentyl)Piperazine
CAS No.	848576-53-4
Molecular Formula	C14H29N3O2
Molecular Weight	271.40 g/mol
Synonyms	tert-Butyl 4-(5-aminopentyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(5-aminopentyl)piperazine; 4-(5-Aminopentyl)-1-Boc-piperazine; N-Boc-4-(5-aminopentyl)piperazine; 1-N-Boc-4-(5-aminopentyl)piperazine; Piperazine, 4-(5-aminopentyl)-, 1-(1,1-dimethylethyl) ester; Boc-4-(5-Aminopentyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(5-Aminopentyl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development from research to commercial scale with GMP-compliant documentation and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.