Description

1-Bromo-2-Methoxy-4-(Trifluoromethoxy)Benzene is a high-value, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique trifluoromethoxy and bromo substituents, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic display materials due to its ability to influence molecular polarity and alignment.
• Organic Ligand & Catalyst Development: Functions as a building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Fluorine Chemistry Research: An essential reagent for studying structure-activity relationships (SAR) in medicinal and materials chemistry, leveraging the properties of fluorine.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring specific halogenated aryl ethers.

Basic Information

Product Name	1-Bromo-2-Methoxy-4-(Trifluoromethoxy)Benzene
CAS No.	848360-85-0
Molecular Formula	C8H6BrF3O2
Molecular Weight	271.04 g/mol
Synonyms	2-Bromo-1-Methoxy-4-(Trifluoromethoxy)Benzene; 4-Bromo-3-Methoxy(Trifluoromethoxy)Benzene; 1-Bromo-2-Methoxy-4-(Trifluoromethoxy)benzene; Benzene, 1-bromo-2-methoxy-4-(trifluoromethoxy)-; 848360-85-0
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methoxy-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.