Description

n-Methoxy-n-Methyl-2,3-Dihydrobenzo[B][1,4]Dioxine-2-Carboxamide is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on novel active ingredients, where its unique fused dioxine-carboxamide structure enables the construction of sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its benzo[1,4]dioxine scaffold for bioactivity.
• Material Science Chemistry: Serves as a building block for creating specialty polymers or organic electronic materials with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies, library synthesis, and exploring new chemical reactions involving Weinreb amide analogs.
• Fine Chemical Synthesis: Utilized in custom synthesis and scale-up projects for producing high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	n-Methoxy-n-Methyl-2,3-Dihydrobenzo[B][1,4]Dioxine-2-Carboxamide
CAS No.	848170-22-9
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	2,3-Dihydro-1,4-benzodioxin-2-carboxylic acid, N-methoxy-N-methylamide; N-Methoxy-N-methyl-2,3-dihydro-1,4-benzodioxine-2-carboxamide; 1,4-Benzodioxin-2-carboxamide, N-methoxy-N-methyl-2,3-dihydro-; 2,3-Dihydrobenzo[1,4]dioxine-2-carboxylic acid N-methoxy-N-methylamide; Weinreb Amide of 2,3-Dihydrobenzo[1,4]dioxine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl-2,3-Dihydrobenzo[B][1,4]Dioxine-2-Carboxamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which could affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.