Description

(Alphas,Alphas)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(R,R)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]Ferrocene is a highly specialized, chiral ferrocenyl diphosphine ligand, CAS number 847997-73-3. This compound is engineered to deliver exceptional enantioselectivity and catalytic activity in asymmetric hydrogenation and other transition metal-catalyzed reactions. It is a critical component for research and production chemists in the pharmaceutical and fine chemical industries who require high-performance, stereoselective catalysts to synthesize complex chiral molecules.

Application

• Asymmetric Hydrogenation Catalysis: A premier ligand for the enantioselective hydrogenation of prochiral olefins, ketones, and imines, crucial for producing chiral intermediates in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Enables the production of single-enantiomer drugs for therapeutic areas such as oncology, cardiology, and central nervous system disorders.
• Fine Chemical Manufacturing: Used in the synthesis of high-value agrochemicals, flavors, and fragrances where precise stereochemistry is required.
• Academic & Industrial R&D: A vital tool for developing new catalytic methodologies and exploring novel reaction pathways in asymmetric synthesis.
• Process Chemistry Optimization: Employed to improve the yield, selectivity, and efficiency of large-scale manufacturing processes for chiral compounds.

Basic Information

Product Name	(Alphas,Alphas)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(R,R)-2,2'-Bis[Di(3,5-Xylyl)Phosphino]Ferrocene
CAS No.	847997-73-3
Molecular Formula	C66H74FeN2P2
Molecular Weight	1021.02 g/mol
Synonyms	(R,R)-TaniaPhos; TaniaPhos (R,R)-isomer; (R,R)-1,1'-Bis(α-(dimethylamino)benzyl)-2,2'-bis(di-3,5-xylylphosphino)ferrocene; JosiPhos ligand derivative; Chiral ferrocenyl diphosphine ligand; Walphos analog; Asymmetric hydrogenation ligand CAS 847997-73-3
EINECS	Contact for details

Quality Control

Every batch of our chiral ligand is produced and analyzed under strict quality control protocols to ensure consistent high performance. Standard specifications include purity assessment by HPLC, confirmation of structure and enantiomeric purity by NMR and chiral analysis, and verification of metal content. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets the exacting standards required for advanced catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or ambient light should be avoided to maintain catalytic efficacy.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity	≥ 99.0% ee
Solubility Test	Soluble in common organic solvents (e.g., Toluene, DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.