Description

3-Chloro-4-(Trifluoromethyl)Phenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing trifluoromethyl and chloro-substituted biphenyl scaffolds.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides where the specific halogen and fluorine substitution pattern enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for constructing sophisticated ligands used in catalysis and molecular recognition.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its structure can tune electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new chemical space.

Basic Information

Product Name	3-Chloro-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	847756-88-1
Molecular Formula	C7H5BClF3O2
Molecular Weight	223.38 g/mol
Synonyms	[3-Chloro-4-(trifluoromethyl)phenyl]boronic acid; (3-Chloro-4-(trifluoromethyl)phenyl)boronic acid; 3-Chloro-4-trifluoromethylbenzeneboronic acid; Boronic acid, B-[3-chloro-4-(trifluoromethyl)phenyl]-; 3-Chloro-alpha,alpha,α-trifluoro-p-tolylboronic acid; 3-Chloro-4-trifluoromethylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.