Description

(S)-tert-Butyl 1-(4-Cyanophenyl)Ethylcarbamate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the development of active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular diseases. This compound is essential for research institutions and manufacturers engaged in the production of enantiomerically pure drugs, where the specific (S)-configuration is critical for biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Protease Inhibitor Development: Used in research and production of inhibitors for enzymes like DPP-4, relevant for diabetes treatments.
• Neurological Drug Synthesis: Serves as a precursor in the manufacture of compounds targeting CNS disorders.
• Asymmetric Synthesis: Employed in chiral pool synthesis and as a starting material for introducing stereogenic centers in complex molecules.
• Peptidomimetics Research: Utilized in the design and synthesis of peptide-like molecules for drug discovery.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	(S)-tert-Butyl 1-(4-Cyanophenyl)Ethylcarbamate
CAS No.	847729-63-9
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	(S)-1-(4-Cyanophenyl)ethyl carbamic acid tert-butyl ester; (S)-tert-Butyl (1-(4-cyanophenyl)ethyl)carbamate; (S)-N-(1-(4-Cyanophenyl)ethyl)carbamic acid tert-butyl ester; (S)-Boc-4-Cyanophenethylamine; (S)-N-Boc-1-(4-Cyanophenyl)ethylamine; (S)-tert-Butyl (1-(4-cyanophenyl)ethyl)carbamate; (S)-1-(4-Cyanophenyl)ethylamine, N-Boc-; (S)-N-(tert-Butoxycarbonyl)-1-(4-cyanophenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 1-(4-Cyanophenyl)Ethylcarbamate is manufactured under strict quality management systems. We provide material with typical chiral purity exceeding 99.0% ee and chemical purity of ≥98.0% (by HPLC), suitable for advanced pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing identity, purity, chiral purity, and residual solvent content are available for every batch. Our quality commitment aligns with ICH guidelines, and we can support projects requiring cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.