Description

tert-Butyl n-[(1R,2R)-Rel-2-Phenylcyclopropyl]Carbamate is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, offering a defined stereochemistry essential for developing active pharmaceutical ingredients (APIs) with high enantiomeric purity. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the construction of complex molecular architectures requiring the specific (1R,2R) stereochemistry for biological activity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the commercial manufacturing of chiral drugs.
• Reference Standard: Utilized as an analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl n-[(1R,2R)-Rel-2-Phenylcyclopropyl]Carbamate
CAS No.	847644-86-4
Molecular Formula	C14H19NO2
Molecular Weight	233.31 g/mol
Synonyms	(1R,2R)-2-Phenylcyclopropanamine N-Boc derivative; tert-Butyl (1R,2R)-2-phenylcyclopropylcarbamate; N-Boc-(1R,2R)-2-phenylcyclopropylamine; (1R,2R)-N-Boc-2-phenylcyclopropanamine; BOC-(1R,2R)-2-Phenylcyclopropylamine; rel-(1R,2R)-2-Phenylcyclopropylcarbamic acid tert-butyl ester; (1R,2R)-rel-2-Phenylcyclopropylcarbamic Acid 1,1-Dimethylethyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[(1R,2R)-Rel-2-Phenylcyclopropyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity determination, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.