Description

Z-D-Dbu-Ome Hcl is a protected amino acid derivative widely utilized as a critical building block in peptide synthesis and pharmaceutical research. This high-purity intermediate is essential for constructing complex peptide chains with specific stereochemistry, ensuring the integrity and bioactivity of the final therapeutic compounds. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the production of novel peptide-based drugs and bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of specific amino acids into peptide sequences.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide therapeutics.
• Bioconjugation: Used in the synthesis of peptide-protein conjugates for targeted drug delivery and diagnostic applications.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new lead compounds with biological activity.
• Biochemical Research: A valuable tool for studying enzyme-substrate interactions, protein folding, and structure-activity relationships (SAR).
• Production of Custom Peptides: Essential for contract research organizations (CROs) and CDMOs manufacturing bespoke peptides for clients.

Basic Information

Product Name	Z-D-Dbu-Ome Hcl
CAS No.	845909-53-7
Molecular Formula	C17H25N3O5 • HCl
Molecular Weight	387.86 g/mol (Free base: 351.40 g/mol)
Synonyms	Z-D-2,4-Diaminobutyric acid methyl ester hydrochloride; Nα-Carbobenzyloxy-D-2,4-diaminobutyric acid methyl ester hydrochloride; Cbz-D-Dab-OMe • HCl; (2R)-2-[[(Benzyloxy)carbonyl]amino]-4-aminobutanoic acid methyl ester hydrochloride; Z-D-Dab-OMe hydrochloride; Z-D-Dbu-OMe • HCl; N-Cbz-D-2,4-diaminobutyric acid methyl ester HCl
EINECS	Contact for details

Quality Control

Our Z-D-Dbu-Ome Hcl is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.