Description

4'-Methoxy-2'-Methyl-2,2,2-Trifluoroacetophenone is a high-purity trifluoromethyl ketone derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both methoxy and trifluoromethyl groups, makes it a versatile intermediate for creating complex molecules with enhanced properties. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic scaffolds for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Ligand and Catalyst Development: Employed as a building block for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research focused on introducing fluorine atoms into complex molecular architectures.

Basic Information

Item	Details
Product Name	4'-Methoxy-2'-Methyl-2,2,2-Trifluoroacetophenone
CAS No.	845823-11-2
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	1-(4-Methoxy-2-methylphenyl)-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(4-methoxy-2-methylphenyl)ethanone; 2-Methyl-4-methoxy-α,α,α-trifluoroacetophenone; 4-Methoxy-2-methyl-α,α,α-trifluoroacetophenone; 4-Methoxy-2-methyl-2,2,2-trifluoroacetophenone; 2'-Methyl-4'-methoxy-2,2,2-trifluoroacetophenone; α,α,α-Trifluoro-4-methoxy-2-methylacetophenone
EINECS	Contact for details

Quality Control

Every batch of 4'-Methoxy-2'-Methyl-2,2,2-Trifluoroacetophenone is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.