Description

1-Aminocyclobutanecarbonitrile Hydrochloride is a versatile and high-purity organic building block essential for advanced chemical synthesis. This compound is valued for its unique strained cyclobutane ring system, which serves as a critical scaffold in medicinal chemistry and materials science research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used as a building block for developing new active ingredients with unique biological activity profiles.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes and tool compounds for studying enzyme mechanisms and protein interactions.
• Peptidomimetic Chemistry: The aminonitrile moiety is valuable for constructing conformationally constrained peptide analogs and macrocycles.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials.
• Academic & Institutional Research: Fundamental reagent for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Aminocyclobutanecarbonitrile Hydrochloride
CAS No.	845821-84-3
Molecular Formula	C5H9N2·HCl
Molecular Weight	132.60 g/mol (Free base: 96.14 g/mol)
Synonyms	1-Aminocyclobutanecarbonitrile HCl; Cyclobutanecarbonitrile, 1-amino-, hydrochloride; 1-Amino-cyclobutanecarbonitrile hydrochloride; 1-Cyano-1-aminocyclobutane hydrochloride; Aminocyclobutanecarbonitrile hydrochloride; (1-Aminocyclobutyl)formonitrile hydrochloride; 1-Aminocyclobutanenitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Aminocyclobutanecarbonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.