Description

(2E)-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-n-(4-Ethoxybenzyl)-3-(Furan-2-Yl)Prop-2-Enamide is a high-purity, advanced pharmaceutical intermediate with a complex molecular architecture. It matters for its role as a critical building block in the synthesis of novel therapeutic agents, particularly in medicinal chemistry research and development. This compound is essential for pharmaceutical companies, contract research organizations (CROs), and academic institutions focused on developing new active pharmaceutical ingredients (APIs) and exploring structure-activity relationships.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used in lead optimization and the exploration of new chemical entities (NCEs) for various therapeutic areas.
• Active Pharmaceutical Ingredient (API) Development: Serves as a sophisticated building block in the development and scale-up of novel APIs.
• Biochemical Research: Employed in studies investigating molecular interactions and biological activity due to its specific functional groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Institutional R&D: Utilized in university and institutional laboratories for advanced organic synthesis and drug discovery programs.

Basic Information

Product Name	(2E)-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-n-(4-Ethoxybenzyl)-3-(Furan-2-Yl)Prop-2-Enamide
CAS No.	845663-03-8
Molecular Formula	C21H25NO5S
Molecular Weight	403.49 g/mol
Synonyms	(E)-N-(1,1-Dioxidotetrahydro-3-thienyl)-N-[(4-ethoxyphenyl)methyl]-3-(2-furanyl)-2-propenamide; (2E)-N-(1,1-Dioxidotetrahydrothiophen-3-yl)-N-(4-ethoxybenzyl)-3-(furan-2-yl)prop-2-enamide; 3-(2-Furanyl)-N-[(4-ethoxyphenyl)methyl]-N-(tetrahydro-1,1-dioxido-3-thienyl)-2-propenamide, (2E)-; 845663-03-8; UNII-0J8V7198Q9; 0J8V7198Q9; (E)-N-(1,1-Dioxido-1lambda6-thiolan-3-yl)-N-[(4-ethoxyphenyl)methyl]-3-(furan-2-yl)prop-2-enamide
EINECS	Contact for details

Quality Control

Our (2E)-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-n-(4-Ethoxybenzyl)-3-(Furan-2-Yl)Prop-2-Enamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity consistent with cGMP guidelines for pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.