Description

Cyclobutane-1,1-Dicarboxylic Acid Monoamide is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. Its unique strained-ring structure and bifunctional reactivity make it valuable for medicinal chemists and process development scientists seeking to create novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and mechanical properties.
• Chemical Biology & Proteomics: Employed as a scaffold or linker for creating chemical probes and affinity tags to study protein function and interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new cyclobutane-based chemistry.
• Custom Synthesis: A starting material for the contract manufacturing of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	Cyclobutane-1,1-Dicarboxylic Acid Monoamide
CAS No.	845621-11-6
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	1,1-Cyclobutanedicarboxylic Acid Monoamide; 1-Carbamoylcyclobutane-1-carboxylic Acid; Cyclobutane-1,1-dicarboxamide (partial); Monoamide of Cyclobutane-1,1-dicarboxylic Acid; 1,1-Cyclobutanedicarboxamide (partial); 845621-11-6; Cyclobutane Monoamide Derivative
EINECS	Contact for details

Quality Control

Our Cyclobutane-1,1-Dicarboxylic Acid Monoamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and potential degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.