Description

4-(Piperidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, nitrogen-containing scaffold with orthogonal protecting groups, enabling precise molecular construction for complex targets. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Building block for creating new pesticides and herbicides with specific biological activity.
• Chemical Research: Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand Development: Used in the preparation of complex ligands for catalysis and molecular recognition applications.
• Peptidomimetics: Incorporation into peptide-like structures to enhance metabolic stability and bioavailability.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and custom synthesis providers.

Basic Information

Product Name	4-(Piperidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	845305-83-1
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	1-Boc-4-(4-piperidinyloxy)piperidine; tert-Butyl 4-(piperidin-4-yloxy)piperidine-1-carboxylate; 4-(1-Piperidinyloxy)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 4-(Piperidin-4-yloxy)piperidine-1-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 4-(4-piperidinyloxy)-1-piperidinecarboxylate; 4-(4-Piperidyloxy)piperidine-1-carboxylic acid tert-butyl ester; Boc-4-(4-piperidyloxy)piperidine
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-4-Yloxy)-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.