Description

4-Dimethylamino-3'-Trifluoromethylbiphenyl is a high-purity, specialized biphenyl derivative featuring both dimethylamino and trifluoromethyl functional groups. This unique molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its conjugated biphenyl core.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the dimethylamino-trifluoromethylbiphenyl moiety into more complex molecular frameworks.
• Chemical Research & Development: A key reagent for medicinal chemistry programs and process chemistry optimization in both academic and industrial laboratories.

Basic Information

Product Name	4-Dimethylamino-3'-Trifluoromethylbiphenyl
CAS No.	844856-48-0
Molecular Formula	C15H14F3N
Molecular Weight	265.27 g/mol
Synonyms	3'-(Trifluoromethyl)-4-(dimethylamino)biphenyl; 4-(Dimethylamino)-3'-(trifluoromethyl)-1,1'-biphenyl; [1,1'-Biphenyl]-4-amine, N,N-dimethyl-3'-(trifluoromethyl)-; N,N-Dimethyl-3'-(trifluoromethyl)-[1,1'-biphenyl]-4-amine; 4-Dimethylamino-3'-trifluoromethyl biphenyl
EINECS	Contact for details

Quality Control

Every batch of 4-Dimethylamino-3'-Trifluoromethylbiphenyl is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality control protocol includes HPLC for assay and impurity profiling, along with spectroscopic identification (NMR, IR). A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.