Description

3-Fluoro-3'-Trifluoromethylbiphenyl is a high-purity fluorinated biphenyl derivative, a key structural motif in advanced material and pharmaceutical chemistry. This compound matters for its role as a sophisticated building block, enabling the introduction of fluorine atoms and biphenyl scaffolds to fine-tune the electronic and steric properties of target molecules. It is needed by R&D and production teams in the pharmaceutical, agrochemical, and organic electronics industries for applications in drug discovery, material science, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of compounds targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorinated biphenyl core contributes to biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, enhancing charge transport and thermal stability.
• Polymer & Resin Modifier: Incorporated into specialty polymers and high-performance resins to improve chemical resistance, thermal properties, and surface characteristics.
• Organic Synthesis Reagent: Acts as a versatile reagent in cross-coupling reactions (e.g., Suzuki, Stille) for constructing complex polyaromatic systems in academic and industrial research.
• Fluorine Chemistry Research: A valuable substrate for studying structure-activity relationships (SAR) and developing new fluorination methodologies in synthetic chemistry.

Basic Information

Product Name	3-Fluoro-3'-Trifluoromethylbiphenyl
CAS No.	844856-46-8
Molecular Formula	C13H8F4
Molecular Weight	240.20 g/mol
Synonyms	[1,1'-Biphenyl]-3-fluoro-3'-(trifluoromethyl); 3-Fluoro-3'-(trifluoromethyl)-1,1'-biphenyl; 3-Fluoro-3'-trifluoromethyl-1,1'-biphenyl; 3-Fluoro-3'-(trifluoromethyl)biphenyl; 3-Fluoro-3'-trifluoromethyl biphenyl; 3-Fluoro-3'-trifluoromethyl diphenyl; Biphenyl, 3-fluoro-3'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3-Fluoro-3'-Trifluoromethylbiphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.