Description

3-(3-Fluorophenoxy)Propanenitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a phenoxy ether linkage and a reactive nitrile group, makes it a valuable precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Polymer Chemistry: Employed as a monomer or modifier to introduce fluorinated aromatic units into polymer backbones, altering material properties.
• Cross-Coupling Reactions: The aromatic ring is amenable to various palladium-catalyzed reactions for creating diverse biaryl structures.
• Nitrile Transformation: The nitrile group can be converted into amides, acids, tetrazoles, or reduced to amines, enabling significant molecular diversification.

Basic Information

Product Name	3-(3-Fluorophenoxy)Propanenitrile
CAS No.	844648-05-1
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	3-(3-Fluorophenoxy)propanenitrile; 3-Fluorophenyl 2-cyanoethyl ether; 2-Cyanoethyl 3-fluorophenyl ether; 3-Fluorophenoxypropionitrile; Propanenitrile, 3-(3-fluorophenoxy)-; 3-(3-Fluorophenoxy)propionitrile
EINECS	Contact for details

Quality Control

Our 3-(3-Fluorophenoxy)Propanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.