Description

3-Bromo-2,4,6-Trifluorobenzotrifluoride is a highly fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and multiple fluorine substituents, makes it a versatile intermediate for introducing specific functionalities into complex molecules. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in medicinal chemistry for lead optimization.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Liquid Crystal & OLED Research: Employed in the synthesis of fluorinated components for display and lighting technologies.
• Cross-Coupling Reactions: The bromine substituent acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Negishi) to create complex biaryl structures.
• Fluorine Chemistry Exploration: A valuable substrate for studying nucleophilic aromatic substitution and other reactions specific to perfluorinated arenes.

Basic Information

Product Name	3-Bromo-2,4,6-Trifluorobenzotrifluoride
CAS No.	844439-00-5
Molecular Formula	C7BrF6
Molecular Weight	276.97 g/mol
Synonyms	1-Bromo-2,4,6-trifluoro-3-(trifluoromethyl)benzene; 2,4,6-Trifluoro-3-(trifluoromethyl)bromobenzene; 3-Bromo-α,α,α,2,4,6-hexafluorotoluene; Benzene, 1-bromo-2,4,6-trifluoro-3-(trifluoromethyl)-; 3-Bromo-2,4,6-trifluoro-α,α,α-trifluorotoluene; 3-Bromo-2,4,6-trifluoro(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2,4,6-Trifluorobenzotrifluoride is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC/HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.