Description

4-Cyano-3-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its role as a versatile Suzuki-Miyaura cross-coupling reagent, enabling the efficient construction of complex biaryl structures. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing fluorinated and cyanated biphenyl motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific fluorinated aromatic structures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for OLEDs and other fluorinated polymers.
• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, a cornerstone of modern medicinal chemistry.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and organoboron chemistry.
• Chemical Biology Probes: Acts as a synthetic handle for creating fluorinated molecular probes and tags used in biochemical research.

Basic Information

Product Name	4-Cyano-3-Fluorophenylboronic Acid
CAS No.	843663-18-3
Molecular Formula	C7H5BFNO2
Molecular Weight	164.93 g/mol
Synonyms	(4-Cyano-3-fluorophenyl)boronic acid; 3-Fluoro-4-cyanophenylboronic acid; B-(4-Cyano-3-fluorophenyl)boronic acid; 4-Cyano-3-fluorobenzeneboronic acid; 843663-18-3; Boronic acid, B-(4-cyano-3-fluorophenyl)-; AKOS005258065
EINECS	Contact for details

Quality Control

Our 4-Cyano-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep the container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.