Description

2-Bromo-3-(3-Chloro-4-Fluorophenyl)-1-Propene is a specialized halogenated organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a key building block in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel material science applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated phenylpropene structure for enhanced biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the creation of novel ligands used in catalytic processes like cross-coupling reactions.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and protein interactions due to its reactive alkene and halogen functionalities.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Bromo-3-(3-Chloro-4-Fluorophenyl)-1-Propene
CAS No.	842140-28-7
Molecular Formula	C9H7BrClF
Molecular Weight	249.51 g/mol
Synonyms	1-Propene, 2-bromo-3-(3-chloro-4-fluorophenyl)-; 3-(3-Chloro-4-fluorophenyl)-2-bromoprop-1-ene; 2-Bromo-1-(3-chloro-4-fluorophenyl)prop-1-ene; (E/Z)-2-Bromo-3-(3-chloro-4-fluorophenyl)prop-1-ene; 842140-28-7; 3-Chloro-4-fluoro-β-bromostyrene
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-(3-Chloro-4-Fluorophenyl)-1-Propene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support our global clients with documentation relevant to their regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.