Description

n-Methoxy-n-Methyl 5-Bromo-2-Chlorobenzamide is a high-value, multi-functional chemical intermediate designed for advanced synthetic chemistry. Its molecular architecture, featuring both bromo and chloro substituents on an aromatic ring coupled with a Weinreb amide moiety, makes it a critical building block for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise, reliable intermediates for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized benzamide core.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Weinreb Amide Applications: Serves as a versatile reagent in organic synthesis for the controlled introduction of ketone or aldehyde groups via nucleophilic addition, preventing over-addition.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where specific halogenated aromatic units are required.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the presence of the bromo substituent.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	n-Methoxy-n-Methyl 5-Bromo-2-Chlorobenzamide
CAS No.	842136-59-8
Molecular Formula	C10H11BrClNO2
Molecular Weight	292.56 g/mol
Synonyms	5-Bromo-2-chloro-N-methoxy-N-methylbenzamide; N-Methoxy-N-methyl-5-bromo-2-chlorobenzamide; 5-Bromo-2-chlorobenzoic acid N-methoxy-N-methylamide; Benzamide, 5-bromo-2-chloro-N-methoxy-N-methyl-; Weinreb amide of 5-bromo-2-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of n-Methoxy-n-Methyl 5-Bromo-2-Chlorobenzamide is produced under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity requirements suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 98.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.