Description

trans-2-(4-Fluoro-3-Methylphenyl)Cyclopentanol CAS NO 835912-96-4 is a chiral, fluorinated cyclopentanol derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in the precise stereochemistry and the presence of both fluorine and methyl substituents on the aromatic ring, which are key motifs for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity building blocks for drug discovery and active ingredient development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of advanced herbicides and fungicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science: Investigated as a monomer or additive for specialty polymers, where its structure can influence material properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in synthetic organic chemistry and fluorine chemistry.

Basic Information

Product Name	trans-2-(4-Fluoro-3-Methylphenyl)Cyclopentanol
CAS No.	835912-96-4
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	trans-2-(4-Fluoro-3-methylphenyl)cyclopentan-1-ol; (1R,2S)-2-(4-Fluoro-3-methylphenyl)cyclopentanol; (1S,2R)-2-(4-Fluoro-3-methylphenyl)cyclopentanol; 2-(4-Fluoro-3-methylphenyl)cyclopentanol (trans); 4-Fluoro-3-methyl-trans-2-cyclopentylphenol; FC-835912; F3MCP
EINECS	Contact for details

Quality Control

Our trans-2-(4-Fluoro-3-Methylphenyl)Cyclopentanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which could affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.