Description

(4-Amino-2,3-Difluorophenyl)Acetic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino and a carboxylic acid functional group on a difluorinated benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving charge transport and thermal stability.
• Polymer Modification: Employed to introduce fluorinated aromatic units into specialty polymers, enhancing their chemical resistance, thermal properties, and dielectric characteristics.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new fluorination chemistry and creating novel molecular libraries.
• Peptide Mimetics & Bio-conjugation: The amino and carboxyl groups allow for its incorporation into peptide chains or use as a linker in bioconjugation strategies for drug delivery systems.

Basic Information

Product Name	(4-Amino-2,3-Difluorophenyl)Acetic Acid
CAS No.	835912-66-8
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	2-(4-Amino-2,3-difluorophenyl)acetic acid; 4-Amino-2,3-difluorobenzeneacetic acid; (4-Amino-2,3-difluorophenyl)ethanoic acid; 2,3-Difluoro-4-aminophenylacetic acid; AA-2,3-DFPA; 835912-66-8; 4-Amino-2,3-difluorophenylacetic acid
EINECS	Contact for details

Quality Control

Every batch of (4-Amino-2,3-Difluorophenyl)Acetic Acid is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.