Description

Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2S)- (9Ci) is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional group array make it a critical building block for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in the development of antiviral, anti-inflammatory, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development and study of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multistep synthesis of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & R&D Laboratories: A crucial reagent for methodological studies in organic chemistry, particularly in stereoselective synthesis and natural product total synthesis projects.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2S)- (9Ci)
CAS No.	834886-30-5
Molecular Formula	C10H15NO3
Molecular Weight	197.23 g/mol
Synonyms	(1S,2S)-2-Cyano-2-hydroxycyclopentanecarboxylic acid 1-methylethyl ester; (1S,2S)-Isopropyl 2-cyano-2-hydroxycyclopentanecarboxylate; (1S,2S)-2-Hydroxy-2-cyanocyclopentanecarboxylic acid isopropyl ester; (1S,2S)-rel-2-Cyano-2-hydroxycyclopentanecarboxylic acid 1-methylethyl ester; Isopropyl (1S,2S)-2-cyano-2-hydroxycyclopentanecarboxylate; (1S,2S)-Cyclopentanecarboxylic acid, 2-cyano-2-hydroxy-, 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our Cyclopentanecarboxylic Acid, 2-Cyano-2-Hydroxy-, 1-Methylethyl Ester, (1S,2S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.