Description

Cyclopentanecarbonitrile, 1-Hydroxy-2-Propyl-, (1S,2S)- (9Ci) is a high-purity, chiral nitrile derivative with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated organic synthesis. Its value lies in providing a stereochemically controlled building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise chirality and functional group compatibility for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential antiviral, anticancer, or central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the construction of enantiomerically pure active ingredients for advanced pesticides and herbicides, where specific stereochemistry can impact biological activity and environmental profile.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands or organocatalysts used in enantioselective transformations.
• Fine Chemical and Specialty Material Production: Employed in the synthesis of complex molecules for flavors, fragrances, and functional materials where the nitrile and alcohol functionalities are valuable.
• Academic and Industrial R&D: A valuable tool for methodological studies in organic chemistry, particularly in reactions involving nitrile groups and stereocenter manipulation.

Basic Information

Product Name	Cyclopentanecarbonitrile, 1-Hydroxy-2-Propyl-, (1S,2S)- (9Ci)
CAS No.	834885-78-8
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(1S,2S)-1-Hydroxy-2-propylcyclopentanecarbonitrile; (1S,2S)-1-Hydroxy-2-propylcyclopentane-1-carbonitrile; 1-Cyclopentanecarbonitrile, 1-hydroxy-2-propyl-, (1S,2S)-; (1S,2S)-1-Hydroxy-2-propyl-1-cyclopentanecarbonitrile; (1S,2S)-2-Propyl-1-hydroxycyclopentanecarbonitrile; Chiral Hydroxypropyl Cyclopentanecarbonitrile; (1S,2S) Isomer of Hydroxypropyl Cyclopentanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarbonitrile, 1-Hydroxy-2-Propyl-, (1S,2S)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.