Description

1-(4-Ethyl-Phenyl)-4,4-Difluoro-Butane-1,3-Dione is a specialized fluorinated diketone compound, identified by CAS number 832741-19-2. This chemical serves as a versatile and critical building block in advanced organic synthesis, particularly valued for introducing difluoromethylene groups into complex molecular architectures. It is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those incorporating fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides where the difluoro group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Used in the preparation of chelating ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Material Science Research: Intermediate for creating fluorinated polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology Probes: Serves as a scaffold for developing fluorescent tags and molecular probes used in diagnostic and biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated diketone chemistry.

Basic Information

Product Name	1-(4-Ethyl-Phenyl)-4,4-Difluoro-Butane-1,3-Dione
CAS No.	832741-19-2
Molecular Formula	C12H12F2O2
Molecular Weight	226.22 g/mol
Synonyms	4'-Ethyl-2,2-difluoroacetophenone; 1-(4-Ethylphenyl)-4,4-difluorobutane-1,3-dione; 4,4-Difluoro-1-(4-ethylphenyl)butane-1,3-dione; 2,2-Difluoro-1-(4-ethylphenyl)ethanone; DFAB-Et (common abbreviation); 4-Ethyl-α,α-difluoroacetophenone; (4-Ethylphenyl)difluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Ethyl-Phenyl)-4,4-Difluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with ISO standards and meets the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.