Description

1-(4-Difluoromethoxy-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring both difluoromethoxy and trifluoromethyl groups, makes it a valuable precursor for creating complex molecules with enhanced physicochemical properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those requiring fluorinated motifs for improved metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where fluorine incorporation can enhance activity and environmental profile.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and coatings with specific thermal, chemical, or surface properties.
• Ligand and Catalyst Development: Employed in the creation of novel chelating ligands and organocatalysts for asymmetric synthesis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in fluorination and the construction of complex fluoroorganic molecules.

Basic Information

Product Name	1-(4-Difluoromethoxy-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	832740-91-7
Molecular Formula	C11H7F5O3
Molecular Weight	282.16 g/mol
Synonyms	4,4,4-Trifluoro-1-[4-(difluoromethoxy)phenyl]butane-1,3-dione; 1-(4-Difluoromethoxyphenyl)-4,4,4-trifluorobutane-1,3-dione; 4-(Difluoromethoxy)phenyl 4,4,4-trifluoroacetoacetate ketone form; DFMP-TFBD; CAS 832740-91-7
EINECS	Contact for details

Quality Control

Our 1-(4-Difluoromethoxy-Phenyl)-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistent performance. Standard quality checks include identity confirmation (IR, NMR), purity assay (HPLC/GC), and control of key impurities. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.