Description

2-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the trifluoromethoxyphenyl moiety.
• Liquid Crystal & OLED Material Development: Employed in the creation of advanced organic electronic materials and liquid crystal compounds for displays.
• Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.
• Catalyst Ligand Synthesis: Used to prepare sophisticated ligand systems for transition metal catalysis.

Basic Information

Product Name	2-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester
CAS No.	832114-04-2
Molecular Formula	C₁₃H₁₆BF₃O₃
Molecular Weight	288.07 g/mol
Synonyms	2-(Trifluoromethoxy)benzeneboronic acid pinacol ester; [2-(Trifluoromethoxy)phenyl]boronic acid pinacol ester; 2-(Trifluoromethoxy)phenylboronic acid neopentyl glycol ester (common alternative); 2-(Trifluoromethoxyphenyl)BPin; 2-Trifluoromethoxyphenyl-Bpin; 2-CF3O-Ph-Bpin; Pinacol 2-(Trifluoromethoxy)phenylboronate
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethoxy)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The pinacol ester group offers improved stability compared to the free boronic acid, but standard handling practices for moisture-sensitive reagents are recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.