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(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene CAS NO 831226-37-0


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CAS No.:831226-37-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene is a highly specialized, chiral ferrocenyl diphosphine ligand designed for asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity and catalytic activity in critical carbon-carbon bond-forming reactions. It is an essential tool for R&D chemists and process engineers in the pharmaceutical and fine chemical industries seeking to develop efficient, stereoselective synthetic routes.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of pharmaceutical intermediates.
  • Catalyst component for asymmetric C-C cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings.
  • Key reagent in the enantioselective synthesis of amino acids, amines, and other bioactive molecules.
  • Used in academic and industrial research for developing novel catalytic methodologies.
  • Employed in the production of advanced materials and specialty chemicals requiring precise stereochemical control.

Basic Information

Product Name (Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene
CAS No. 831226-37-0
Molecular Formula C58H60FeN2P2
Molecular Weight 879.88 g/mol
Synonyms (S,S)-Alphar-Ferrocene; Josiphos SL-J009-1; (S,S)-1,1'-Bis[α-(Dimethylamino)benzyl]-2,2'-bis[bis(2-methylphenyl)phosphino]ferrocene; (S,S)-2,2'-Bis[bis(2-methylphenyl)phosphino]-1,1'-bis[α-(dimethylamino)benzyl]ferrocene; (S,S)-Alphar-Ferrocene Ligand; (S,S)-Alphar-Fc; Chiral Josiphos-type ligand; Ferrocenyl diphosphine ligand SL-J009-1
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Quality Control

Every batch of our chiral ligand is produced and tested under strict quality control protocols to ensure consistent high purity and performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity confirmation. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and catalytic activity.

Specification

Item Specification
Appearance Orange to red powder or crystals
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Loss on Drying ≤ 1.0 %
Residue on Ignition ≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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