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(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene CAS NO 831226-37-0
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CAS No.:831226-37-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene is a highly specialized, chiral ferrocenyl diphosphine ligand designed for asymmetric catalysis. This compound matters for its exceptional ability to induce high enantioselectivity and catalytic activity in critical carbon-carbon bond-forming reactions. It is an essential tool for R&D chemists and process engineers in the pharmaceutical and fine chemical industries seeking to develop efficient, stereoselective synthetic routes.
Application
- As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of pharmaceutical intermediates.
- Catalyst component for asymmetric C-C cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings.
- Key reagent in the enantioselective synthesis of amino acids, amines, and other bioactive molecules.
- Used in academic and industrial research for developing novel catalytic methodologies.
- Employed in the production of advanced materials and specialty chemicals requiring precise stereochemical control.
Basic Information
| Product Name | (Alphar,Alphar)-1,1'-Bis[α-(Dimethylamino)Benzyl]-(S,S)-2,2'-Bis[Bis(2-Methylphenyl)Phosphino]Ferrocene |
| CAS No. | 831226-37-0 |
| Molecular Formula | C58H60FeN2P2 |
| Molecular Weight | 879.88 g/mol |
| Synonyms | (S,S)-Alphar-Ferrocene; Josiphos SL-J009-1; (S,S)-1,1'-Bis[α-(Dimethylamino)benzyl]-2,2'-bis[bis(2-methylphenyl)phosphino]ferrocene; (S,S)-2,2'-Bis[bis(2-methylphenyl)phosphino]-1,1'-bis[α-(dimethylamino)benzyl]ferrocene; (S,S)-Alphar-Ferrocene Ligand; (S,S)-Alphar-Fc; Chiral Josiphos-type ligand; Ferrocenyl diphosphine ligand SL-J009-1 |
| EINECS | Contact for details |
Quality Control
Every batch of our chiral ligand is produced and tested under strict quality control protocols to ensure consistent high purity and performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity confirmation. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and process chemistry applications.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and catalytic activity.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red powder or crystals |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Chiral Purity (HPLC) | ≥ 99.0% ee |
| Loss on Drying | ≤ 1.0 % |
| Residue on Ignition | ≤ 0.5 % |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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