Description

Benzenebutanoic Acid, 2-Amino-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-γ-Oxo-, (αs)- is a specialized, high-purity amino acid derivative designed for advanced pharmaceutical research and synthesis. This compound serves as a critical building block in the development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in peptide synthesis and medicinal chemistry.

Application

• Peptide Synthesis: A key protected amino acid derivative for solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Serves as a crucial building block in the research and development of new therapeutic peptides and small molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the synthesis of complex molecular libraries for drug discovery.
• Bioconjugation: Employed in the synthesis of peptide-drug conjugates and other bioconjugates for targeted therapies.
• Protecting Group Strategy: The Fmoc (9-fluorenylmethoxycarbonyl) protecting group is central to its use in orthogonal peptide synthesis protocols.

Basic Information

Product Name	Benzenebutanoic Acid, 2-Amino-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-γ-Oxo-, (αs)-
CAS No.	831210-89-0
Molecular Formula	C26H24N2O5
Molecular Weight	444.48 g/mol
Synonyms	Fmoc-Asp(OtBu)-OH; Fmoc-L-Aspartic acid 4-tert-butyl ester; N-α-Fmoc-L-aspartic acid 4-tert-butyl ester; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)succinic acid 4-tert-butyl ester; Fmoc-Asp(OtBu)-OH; N-Fmoc-L-aspartic acid 4-tert-butyl ester; Fmoc-Aspartate(OtBu); Fmoc-Asp(OtBu)-OH
EINECS	Contact for details

Quality Control

Our Benzenebutanoic Acid, 2-Amino-α-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-γ-Oxo-, (αs)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure compliance with research-grade and cGMP standards where applicable. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.