Description

5-Bromo-2-Pyrimidineacetonitrile is a versatile brominated pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a reactive bromine atom and a nitrile functional group, makes it an invaluable intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: A building block for creating novel organic electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for use in custom synthesis projects and scale-up activities.

Basic Information

Product Name	5-Bromo-2-Pyrimidineacetonitrile
CAS No.	831203-15-7
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	2-(5-Bromopyrimidin-2-yl)acetonitrile; (5-Bromo-2-pyrimidinyl)acetonitrile; 5-Bromo-2-pyrimidineacetonitrile; 5-Bromopyrimidine-2-acetonitrile; Acetonitrile, (5-bromo-2-pyrimidinyl)-; 831203-15-7; 5-Bromo-2-pyrimidylacetonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Pyrimidineacetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.