Description

2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetonitrile is a high-purity, multi-functional pyridine derivative building block essential for advanced organic synthesis. This compound is valued for its unique halogenated structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and specialty polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the presence of the bromine atom.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and the development of molecular probes.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects.

Basic Information

Product Name	2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetonitrile
CAS No.	831203-14-6
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	(5-Bromo-3-fluoro-2-pyridinyl)acetonitrile; 2-(5-Bromo-3-fluoropyridin-2-yl)ethanenitrile; 5-Bromo-3-fluoro-2-pyridineacetonitrile; 2-Pyridineacetonitrile, 5-bromo-3-fluoro-; 831203-14-6; 5-Bromo-3-fluoropicolinonitrile (incorrect but common search term); Acetonitrile, (5-bromo-3-fluoro-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-3-Fluoropyridin-2-Yl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.