Description

R-(-)-Deprenyl n-Oxide Hydrochloride is a high-purity chiral intermediate and metabolite of the well-known compound selegiline. This product matters for its critical role in pharmaceutical research and development, particularly in the study of neuropharmacology and the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in developing treatments for neurological disorders and producing high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of advanced selegiline analogs and other neuroactive compounds.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and metabolic studies of selegiline (R-(-)-deprenyl).
• Neurological Research: Employed in preclinical research to investigate the mechanisms of monoamine oxidase-B (MAO-B) inhibition and related pathways.
• Process Chemistry: Serves as a starting material or intermediate in the development and scale-up of enantioselective synthetic routes.
• Quality Control & Analytical Testing: Utilized as a certified reference material (CRM) for HPLC, LC-MS, or NMR method development and validation in QC laboratories.

Basic Information

Product Name	R-(-)-Deprenyl n-Oxide Hydrochloride
CAS No.	830318-01-9
Molecular Formula	C13H18ClNO2
Molecular Weight	255.74 g/mol
Synonyms	(R)-(-)-Deprenyl N-Oxide HCl; (R)-Selegiline N-Oxide Hydrochloride; (R)-N,α-Dimethyl-N-(2-propynyl)phenethylamine N-Oxide Hydrochloride; (-)-Deprenyl N-Oxide Hydrochloride; R-(-)-N-Methyl-N-(1-phenyl-2-propyl)-N-propargylamine N-Oxide Hydrochloride; L-Deprenyl N-Oxide HCl; (R)-N-Methyl-N-(2-phenylpropyl)prop-2-yn-1-amine N-Oxide Hydrochloride
EINECS	Contact for details

Quality Control

Our R-(-)-Deprenyl n-Oxide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.