Description

(R)-(+)-4-[2-(Diphenylphosphino)-1-Naphthalenyl]-n-[(R)-1-Phenylethoxy]Phthalazine, Min. 97% (R,R)-o-Pinap is a high-purity, chiral phosphine-oxazoline ligand, a critical component in asymmetric catalysis. Its primary value lies in enabling highly enantioselective transformations, which are essential for the efficient synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is specifically needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control. The compound is supplied with a minimum purity of 97% (R,R)-enantiomer to ensure consistent and reliable catalytic performance.

Application

• As a chiral ligand for asymmetric hydrogenation reactions in pharmaceutical API synthesis.
• Catalyst component for enantioselective C-C bond formation (e.g., Heck, Suzuki-Miyaura cross-couplings).
• Key reagent in the stereoselective synthesis of chiral amines, alcohols, and carboxylic acid derivatives.
• Research tool for developing new asymmetric catalytic methodologies in academic and industrial laboratories.
• Production of optically pure intermediates for agrochemicals and specialty chemicals.
• Use in transition metal catalysis for creating high-value, complex molecular architectures.

Basic Information

Product Name	(R)-(+)-4-[2-(Diphenylphosphino)-1-Naphthalenyl]-n-[(R)-1-Phenylethoxy]Phthalazine, Min. 97% (R,R)-o-Pinap
CAS No.	828927-95-3
Molecular Formula	C₃₈H₂₉N₂OP
Molecular Weight	560.62 g/mol
Synonyms	(R,R)-o-Pinap; (R)-(+)-o-Pinap; (R,R)-2-[2-(Diphenylphosphino)-1-naphthyl]-4-[(R)-1-phenylethyl]-4,5-dihydrooxazole; (R,R)-2-[2-(Diphenylphosphino)naphthalen-1-yl]-4-[(R)-1-phenylethyl]-4,5-dihydrooxazole; (R,R)-PINAP; o-PINAP ligand; Chiral PINAP ligand; Asymmetric PINAP ligand
EINECS	Contact for details

Quality Control

Every batch of our (R,R)-o-Pinap ligand undergoes rigorous analytical testing to ensure it meets the stringent purity and enantiomeric excess requirements for catalytic applications. Our quality protocols include advanced chromatographic and spectroscopic methods to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (HPLC), and other critical parameters is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 97.0%
Enantiomeric Purity (HPLC)	Min. 97.0% (R,R)-enantiomer
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.