Description

3-Bromo-n-Methyl-n-Boc-Propylamine is a high-value, protected amine building block extensively used in advanced organic synthesis. This compound is critical for the controlled introduction of functionalized amine moieties, enabling the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as medicinal chemistry, peptide mimetics, and catalyst ligand synthesis.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing tertiary amine functionalities.
• Peptidomimetics & PROTACs: Serves as a versatile linker or spacer component in the design of peptide mimics and Proteolysis Targeting Chimeras (PROTACs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific amine-based side chains.
• Ligand & Catalyst Development: Employed for the preparation of specialized nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology Probes: Facilitates the creation of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: An essential raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Bromo-n-Methyl-n-Boc-Propylamine
CAS No.	828272-19-1
Molecular Formula	C9H18BrNO2
Molecular Weight	252.15 g/mol
Synonyms	1-Boc-3-bromo-N-methylpropylamine; tert-Butyl (3-bromopropyl)(methyl)carbamate; N-Boc-N-Methyl-3-bromopropylamine; 3-Bromo-N-methyl-N-[(2-methyl-2-propanyl)oxy]carbonyl]-1-propanamine; (3-Bromopropyl)(methyl)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyl)-N-methyl-3-bromopropylamine; Boc-N-Me-3-bromopropylamine; N-Methyl-N-Boc-3-bromopropylamine
EINECS	Contact for details

Quality Control

Our 3-Bromo-n-Methyl-n-Boc-Propylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.