Description

1,4-Methanonaphthalene-5-Carbonitrile,1,4,4A,5,8,8A-Hexahydro-5-Methyl-8-Oxo-,(1R,4S,4Ar,5R,8As)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, functionalized polycyclic structure, which serves as a critical building block in modern synthetic organic chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly in medicinal chemistry research.
• Organic Synthesis Building Block: Utilized in constructing complex polycyclic frameworks for novel chemical entities in academic and industrial R&D.
• Asymmetric Catalysis Research: Serves as a substrate or a precursor for ligands in studies exploring new catalytic methodologies.
• Fine Chemical Production: Used in the manufacture of specialty chemicals requiring a specific, high-value stereochemical core.
• Reference Standard: Employed as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1,4-Methanonaphthalene-5-Carbonitrile,1,4,4A,5,8,8A-Hexahydro-5-Methyl-8-Oxo-,(1R,4S,4Ar,5R,8As)-Rel-(9Ci)
CAS No.	828248-62-0
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	(1R,4S,4aR,5R,8aS)-1,4,4a,5,8,8a-Hexahydro-5-methyl-8-oxo-1,4-methanonaphthalene-5-carbonitrile; rel-(1R,4S,4aR,5R,8aS)-1,4,4a,5,8,8a-Hexahydro-5-methyl-8-oxo-1,4-methanonaphthalene-5-carbonitrile; 5-Cyano-5-methyl-1,4,4a,5,8,8a-hexahydro-1,4-methanonaphthalen-8-one; 828248-62-0; (1R,4S,4aR,5R,8aS)-5-Methyl-8-oxo-1,4,4a,5,8,8a-hexahydro-1,4-methanonaphthalene-5-carbonitrile
EINECS	Contact for details

Quality Control

Our 1,4-Methanonaphthalene-5-Carbonitrile,1,4,4A,5,8,8A-Hexahydro-5-Methyl-8-Oxo-,(1R,4S,4Ar,5R,8As)-Rel-(9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and chiral purity analysis, to ensure identity, strength, quality, and purity. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.