Description

1,1-Diethyl 3,3-Difluorocyclobutane-1,1-Dicarboxylate is a high-value fluorinated cyclobutane derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluorocyclobutane core, makes it an essential intermediate for developing novel compounds with tailored properties. This product is primarily targeted at research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and pesticides, where the difluorocyclobutane moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the synthesis of specialty polymers and advanced materials, where fluorination improves thermal stability and chemical resistance.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research exploring the effects of gem-difluoro substitution on cyclobutane ring systems and reactivity.

Basic Information

Product Name	1,1-Diethyl 3,3-Difluorocyclobutane-1,1-Dicarboxylate
CAS No.	827032-79-1
Molecular Formula	C11H16F2O4
Molecular Weight	250.24 g/mol
Synonyms	Diethyl 3,3-difluorocyclobutane-1,1-dicarboxylate; 3,3-Difluorocyclobutane-1,1-dicarboxylic Acid Diethyl Ester; 1,1-Bis(ethoxycarbonyl)-3,3-difluorocyclobutane; Ethyl 3,3-Difluorocyclobutane-1,1-Dicarboxylate; Diethyl 3,3-Difluoro-1,1-cyclobutanedicarboxylate; 827032-79-1; 1,1-Cyclobutanedicarboxylic acid, 3,3-difluoro-, 1,1-diethyl ester
EINECS	Contact for details

Quality Control

Our 1,1-Diethyl 3,3-Difluorocyclobutane-1,1-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.