Description

1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Gadolinium Salt) is a high-purity, paramagnetic lipid conjugate designed for advanced biomedical research and diagnostic applications. This specialized compound is critical for developing targeted contrast agents and drug delivery systems due to its unique ability to chelate gadolinium within a phospholipid structure. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and medical imaging sectors for applications in molecular imaging, theranostics, and liposome formulation.

Application

• Magnetic Resonance Imaging (MRI) Contrast Agents: Serves as a key building block for synthesizing targeted and responsive MRI contrast agents, enhancing image contrast for specific tissues or biomarkers.
• Liposome and Nanoparticle Functionalization: Used to incorporate gadolinium chelates into the membrane of liposomes or the surface of nanoparticles for traceable drug delivery and diagnostic systems.
• Molecular Imaging Probes: Enables the development of advanced probes for multimodal imaging, combining MRI with other techniques like fluorescence.
• Theranostic Platform Development: Integral in creating platforms that combine diagnostic imaging and therapeutic capabilities within a single agent.
• Bioconjugation and Targeting: The phospholipid structure allows for further conjugation with targeting ligands like antibodies or peptides for site-specific imaging.
• Research & Development: Employed in academic and industrial R&D for studying membrane interactions, contrast agent pharmacokinetics, and novel diagnostic formulations.

Basic Information

Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Gadolinium Salt)
CAS No.	827020-81-5
Molecular Formula	C49H91GdN5O17P
Molecular Weight	~1248.58 g/mol
Synonyms	DMPE-DTPA(Gd); 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine-N-diethylenetriaminepentaacetic acid gadolinium salt; Gd-DTPA-DMPE; DMPE-DTPA Gadolinium Chelate; DMPE-DTPA-Gd; Phospholipid-DTPA-Gd conjugate; DTPA-bis(stearylamide) Gadolinium Salt (related analog); DMPE-DTPA (Gd complex)
EINECS	Contact for details

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phosphoethanolamine-n-Diethylenetriaminepentaacetic Acid (Gadolinium Salt) is manufactured under strict quality systems suitable for research and development use. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key specifications such as assay, residual solvents, and heavy metal content are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake. The product should be handled in accordance with good laboratory practices for chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Gadolinium Content	Specification available upon request
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Water Content (KF)	< 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.