Description

Cyclobutanecarboxamide, n-(3-Fluoro-4-Methylphenyl)- (9Ci) is a high-purity, fluorinated organic compound with the CAS number 826999-57-9. This specialized chemical serves as a critical pharmaceutical intermediate and research building block for the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its unique cyclobutane and fluorinated aryl motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used as a building block for synthesizing novel herbicides, fungicides, and insecticides, leveraging the metabolic stability often imparted by the fluorine substituent.
• Chemical Biology Probe: Employed in academic and industrial research to create tool compounds for studying enzyme function, receptor binding, and other biological pathways.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of active pharmaceutical ingredients (APIs) requiring this specific molecular scaffold.

Basic Information

Product Name	Cyclobutanecarboxamide, n-(3-Fluoro-4-Methylphenyl)- (9Ci)
CAS No.	826999-57-9
Molecular Formula	C12H14FNO
Molecular Weight	207.25 g/mol
Synonyms	N-(3-Fluoro-4-methylphenyl)cyclobutanecarboxamide; 3-Fluoro-4-methyl-N-(cyclobutanecarbonyl)aniline; Cyclobutanecarboxylic acid (3-fluoro-4-methylphenyl)amide; 826999-57-9; FC-827; Amide, N-(3-fluoro-4-methylphenyl)cyclobutanecarbox-; Cyclobutanecarboxamide, N-(3-fluoro-4-methylphenyl)-
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxamide, n-(3-Fluoro-4-Methylphenyl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to ensure product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.