Description

(4-Fluoro-2-Formylphenyl)Boronic Acid is a high-value, multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated aromatic ring, makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as Suzuki-Miyaura cross-coupling and as a precursor for heterocyclic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Suzuki-Miyaura Cross-Coupling Reagent: Essential for forming carbon-carbon bonds to create biaryl structures, a common motif in medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Organic Electronic Materials: Employed in the research and development of organic light-emitting diodes (OLEDs) and semiconductors, where fluorinated units improve charge transport.
• Chemical Biology Probes: Utilized in the design of molecular probes and sensors for studying biological processes due to its reactive handles for bioconjugation.

Basic Information

Item	Details
Product Name	(4-Fluoro-2-Formylphenyl)Boronic Acid
CAS No.	825644-26-6
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	2-Formyl-4-fluorophenylboronic acid; 4-Fluoro-2-formylbenzeneboronic acid; (4-Fluoro-2-formylphenyl)boronic acid; 2-Borono-5-fluorobenzaldehyde; 5-Fluoro-2-formylphenylboronic acid; 4-Fluoro-2-carboxybenzaldehyde boronic acid (tautomer); 4-Fluoro-2-formylbenzeneboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our (4-Fluoro-2-Formylphenyl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.