Description

(+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane CAS NO 824395-67-7 is a high-purity, chiral bisphosphine ligand essential for asymmetric catalysis. Its primary value lies in enabling highly enantioselective transformations, which are critical for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is specifically needed by research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical synthesis.
• Catalyst component for enantioselective C-C and C-X bond-forming reactions.
• Critical for the production of chiral active pharmaceutical ingredients (APIs) and intermediates.
• Use in asymmetric synthesis for agrochemicals and flavors & fragrances.
• Research tool in academic and industrial settings for developing new catalytic methodologies.
• Key component in catalyst systems for the synthesis of enantiomerically pure fine chemicals.

Basic Information

Product Name	(+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane
CAS No.	824395-67-7
Molecular Formula	C34H32P2
Molecular Weight	502.56 g/mol
Synonyms	(S,S)-Ph-BPE; (S,S)-1,2-Bis(2,5-diphenylphospholano)ethane; (2S,2'S,5S,5'S)-1,1'-(Ethane-1,2-diyl)bis(2,5-diphenylphospholane); Ph-BPE ligand; (S,S)-Bisphospholane Ethane; (S,S)-1,2-Bis[(2S,5S)-2,5-diphenylphospholano]ethane; (+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane
EINECS	Contact for details

Quality Control

Our (+)-1,2-Bis((2S,5S)-2,5-Diphenylphospholano)Ethane is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity for sensitive catalytic applications. Each batch is analyzed using advanced techniques including NMR and HPLC to verify identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.