Description

tert-Butyl 3-(Methoxy(Methyl)Carbamoyl)Azetidine-1-Carboxylate is a high-purity, protected azetidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used in the exploration of structure-activity relationships (SAR) and the construction of novel heterocyclic scaffolds.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Peptidomimetics & Bioactive Molecule Synthesis: The azetidine and carbamate functionalities make it valuable for creating conformationally constrained analogs of peptides.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with novel modes of action.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific projects requiring specialized intermediates.

Basic Information

Product Name	tert-Butyl 3-(Methoxy(Methyl)Carbamoyl)Azetidine-1-Carboxylate
CAS No.	820971-67-3
Molecular Formula	C12H22N2O4
Molecular Weight	258.32 g/mol
Synonyms	1-Boc-3-[(N-methoxy-N-methyl)carbamoyl]azetidine; 1-(tert-Butoxycarbonyl)-3-[(methoxy(methyl)amino)carbonyl]azetidine; 3-[(Methoxy(methyl)carbamoyl)]azetidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-((methoxy(methyl)carbamoyl))azetidine-1-carboxylate; Azetidine-1-carboxylic acid, 3-[(methoxy(methyl)amino)carbonyl]-, 1,1-dimethylethyl ester; Boc-3-Weinreb-amido-azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(Methoxy(Methyl)Carbamoyl)Azetidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.