Description

2-Azetidinone,3-Amino-4-Methyl-,(3S,4R)-(9Ci) is a high-value, stereochemically defined β-lactam building block. This compound matters as a critical chiral synthon for the research and development of novel pharmaceuticals, particularly β-lactam antibiotics and enzyme inhibitors. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures with precise stereochemistry. CAS number 820253-34-7 identifies this specific stereoisomer.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel β-lactam antibiotics, including penems and carbapenems.
• Medicinal Chemistry Research: Building block for structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting bacterial enzymes.
• Enzyme Inhibitor Synthesis: Core scaffold for designing and synthesizing potent inhibitors of serine proteases and other enzymes.
• Process Chemistry: Used in route scouting and scale-up for the commercial production of advanced active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Valuable intermediate for creating complex, stereochemically pure molecules for various high-value applications.

Basic Information

Product Name	2-Azetidinone,3-Amino-4-Methyl-,(3S,4R)-(9Ci)
CAS No.	820253-34-7
Molecular Formula	C4H8N2O
Molecular Weight	100.12 g/mol
Synonyms	(3S,4R)-3-Amino-4-methylazetidin-2-one; (3S,4R)-3-Amino-4-methyl-2-azetidinone; 3-Amino-4-methylazetidin-2-one, (3S,4R)-; 4-Methyl-3-amino-2-azetidinone; β-Amino-β-methyl-β-lactam; (3S-cis)-3-Amino-4-methyl-2-azetidinone; Chiral β-lactam building block; 2-Azetidinone, 3-amino-4-methyl-, (3S,4R)-
EINECS	Contact for details

Quality Control

Our 2-Azetidinone,3-Amino-4-Methyl-,(3S,4R)-(9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.